How is hla typing done

IN US. Skip to content. Book Test Now. Similar test Chimerism. Why do you need the test? Your immune system uses these markers to recognize which cells belong in your body and which do not. How donors and patients are matched. You have many HLA markers. A sample of blood is taken by inserting a needle into a vein in your arm. Sometimes a swab of cells is taken from inside of your cheek called a buccal swab for testing. No special preparation is needed for either method.

The results from HLA testing will let the doctors know whether there is a good match for a stem cell transplant. Human leukocyte antigen HLA testing. Why HLA testing is done. HLA antigens are cell membrane glycoproteins with key roles in the initiation of the immune response. Different DNA-based molecular techniques are used depending on the clinical application. Bone marrow transplantation requires a high-resolution typing to determine the HLA alleles.

Determination of HLA phenotypes is also applied to vaccine development, studies of disease associations and as companion diagnostics for the safe and effective use of therapeutic products. This technology uses the polymerase chain reaction PCR to amplify the locus of interest.

This technology uses PCR to amplify the locus of interest.